Why choose Genova Diagnostics' Genomic Products?
Precision medicine, also called personalized medicine, is an individualized approach to patient care taking into account genetics, lifestyle, and environmental factors. Single Nucleotide Polymorphisms, or SNPs, are genetic variants that may predispose your patients to numerous chronic diseases. Testing can help clinicians identify a patient’s genetic predispositions and tailor therapeutics accordingly.
- Specialized genomic testing can provide a glimpse into a patient’s potential health future and help you influence the ultimate outcome.
- A simple cheek swab can be conveniently collected at home.
- Educational report commentary is specific to the SNP finding, including health implications and clinical management considerations.
- Clinical Information
- Patient Information
- Test Preparation
- Support Materials
DetoxiGenomic® Profile and a la carte SNPs to assess risk
Who can benefit from SNP testing?Researchers have identified thousands of SNPs that relate to almost every chronic disease. Truth is, everybody has SNPs. SNPs are common and generally do not result in life-threatening presentations like genetic mutations, which are rare. SNPs are more subtle and act by reducing cellular functions and ultimately an optimal quality of life. Genomic testing can minimize risk by identifying hidden gene polymorphisms that may promote chronic disease. Many people mistakenly assume that the presence of a SNP means they are destined to experience the associated disease. Fortunately, most genes have flexible expressions and often are influenced by modifiable environmental, diet, and lifestyle factors.
In some instances, genotypic SNP testing may prompt phenotypic monitoring of associated biomarkers. For example, if a patient has a polymorphism for MTHFR, homocysteine may be more closely monitored.
SNP testing may be appropriate for patients with:
Chronic conditions that resist treatment
Family history of cardiovascular disease, mood disorders, Alzheimer’s, cancer, or autoimmune disease
Inflammatory conditions
Cardiovascular disease
Mood disorders
Osteoporosis
Metabolic disorders (insulin resistance)
Chemical sensitivity
Asthma and lung problems
Cognitive decline
DetoxiGenomic Profile evaluates over 20 SNPs related to phase 1 and phase 2 detoxification pathways. These SNPS are associated with increased risk of impaired detoxification capacity especially when exposed to environmental toxins. It also identifies individuals potentially susceptible to adverse drug reactions. See sample report for list of SNPs.
A la carte SNPs
- ApoE - Apolipoprotein E is involved in lipid metabolism and certain polymorphisms can result in increased cardiovascular disease risk and Alzheimer’s disease.1,2
- COMT - Catechol-O-Methyltransferase polymorphisms can result in reduced enzyme activity associated with neuropsychiatric disorders, impaired estrogen metabolism, and increased sensitivity to pain.3,4
- GSTP1 or GSTM1 - Glutathione S-Transferase polymorphisms are associated with a decreased ability to detoxify a majority of substances, which can result in oxidative stress and chronic disease risk.5
- MTHFR (C677T, A1298C) - Methyl tetrahydrofolate Reductase - Polymorphisms of this enzyme can disrupt the metabolism of homocysteine, resulting in its accumulation as well as impaired methylation. The presence of these SNPs can increase risk of cardiovascular disease, blood vessel damage, thrombosis (blood clots), stroke, and degenerative aging.6
- SOD2 - Superoxide Dismutase is an antioxidant enzyme and polymorphisms are associated with reduced SOD activity, increasing risk of oxidative stress.7,8
- TNFα - Tumor Necrosis Factor-alpha is a proinflammatory cytokine and polymorphisms are associated with inflammation, oxidative stress, and numerous disease implications.9
- VDR - Vitamin D Receptor polymorphisms are associated with decreased bone density and osteoporosis.10
SNPs available as add-ons - to other profiles including
- NutrEval and Metabolomix+ – MTHFR, COMT, ApoE, TNF-α
- Methylation Panel – MTHFR, COMT, CBS, MTRR, MAT1A, SHMT1, MTR, BHMT, GNMT
- Essential Estrogens – CYP1B1, MTHFR, COMT, VDR
How it Works
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Book Consultation
Schedule a consultation to discuss your health concerns. I will help determine if specialized testing could provide insights into your symptoms and conditions. If beneficial, I will recommend an appropriate test and order a collection kit.
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Receive Collection Kit
The test kit can be shipped directly to your home or you can pick it up at my office, whichever you prefer. The kit contains detailed instructions and materials for collecting your samples comfortably.
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Provide Samples
Follow the instructions to collect your samples. You can complete this step privacy at home or come to my office if you need assistance. Be sure to provide all requested details to ensure accurate results.
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Send to Lab
Use the prepaid shipping label to send your samples to the processing lab. I track the results and contact you as soon as they are available. No need to worry about following up.
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Review Results
During a follow-up consultation, I will interpret your test results, explain what they mean, and work with you to develop a tailored health plan based on your results. My goal is to provide insights and solutions to help you feel your best.
Frequently Asked Questions
Review information on the Test Preparation tab above for details on how medications and supplements may impact this test.
We provide a variety of testing services, and some of them may or may not be covered by your insurance plan. Once your physician has ordered a Genova Diagnostics test for you, you can submit the CPT codes for your test to your commercial insurance plan to determine coverage. For information about billing options, please visit the Billing Information page.
Support guides, charts, and additional aids can be found on the Support Materials tab. Additional educational materials can be found in our Learning Library. Genova also offers complimentary Medical Education Consultations for healthcare providers. Schedule consults online by signing in to your myGDX account.
Book Your Consultation Today
During your first 60-minute functional televisit, we will try to figure out what’s causing your current health problems. Contact us today at Internal Healing and Wellness MD in the Houston area and The Woodlands, we will make sure to provide you with a personalized functional medicine-based treatment plan so that you can begin working towards your goal of a better, healthier life.
Contact Us
Start Your Holistic Wellness Journey Today
In search of a functional medicine doctor in The Woodlands? Dr. Khan and his experienced team are at your service, ready to help you make life-changing strides toward your health and wellness goals.
Contact Info
Our Location
255 Ed English Dr
Suite A
Shenandoah, TX 77385
Our Schedule
9AM-5PM Monday - Friday
Get In Touch
For functional medicine inquiries, contact our experienced functional medicine doctors. We take a holistic approach to improving health and well-being.